OTOH...Two different sources
are saying that Doctor Strange has already been cast, and it's not Depp at all but, IMO, an inspired choice. Someone who has already proven he can play a bit of a prick who can learn a lesson, with a clear sense of humor and good looks. Someone who hasn't been mentioned here yet, but who can absolutely nail this part.
Depp felt like a safe choice. This one just feels right.